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Symbol: Cebpb Name: CCAAT/enhancer binding protein (C/EBP), beta Alias: C/EBPbeta Entrez gene ID: 12608 Ensembl gene ID: ENSMUSG00000056501 Species: Mouse (Taxid: 10090) Functional description: Transcription factor involved in fat metabolism; Involved in interleukin-6 signal transduction, including the transcriptional activation of acute-phase genes. Functions in brown adipose tissue (BAT) differentiation. [UniProt] Observation: Replacing the Cebpa gene by Cebpb increases mean lifespan by about 20% [15289464]. C/ebpalpha(beta/beta) animals consume more food but weight less than controls [10982846], and have a slightly elevated body temperature (0.3-0.5 degree Celsius) [15289464]. Interventions: Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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