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Symbol: RPL20B Name: Ribosomal Protein of the Large subunit 20B Alias: RPL18A1;L18B;L20B Entrez gene ID: 854489 Ensembl gene ID: YOR312C Species: Yeast (Taxid: 4932) Functional description: Rpl20bp; Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein [Source:SGD;Acc:S000005839] [Ensembl] Observation: Deletion of RPL20B increases mean replicative lifespan by 35 - 50% [19030232] to 40 - 50% [18423200] in the alpha and a strains. While deletion of RPL20B non-significantly increases mean replicative lifespan by 3% in the ORF collection, it significantly by 36% the remade strain [22377630]. RPL20b deletion extends mean, median and maximum lifespan by 71, 89 and 82%, respectively [23167605]. Lifespan extension by RPL20B deletion is Hac1, Sir2 and Fob1 independent, but requires Gcn4 [18423200; 21902802]. Assays: Replicative Lifespan Mean: +35 to +71 Median: +89 Maximum: +82 Classification: References: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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