RPL1B

Symbol: RPL1B
Name: Ribosomal Protein of the Large subunit 1B
Alias: SSM2;L1B
Entrez gene ID: 852742
Ensembl gene ID: YGL135W
Species: Yeast (Taxid: 4932)

Functional description:
Rpl1bp; N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Ap and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal [Source:SGD;Acc:S000003103] [Ensembl]

Observation:

RPL1B deletion increases mean replicative lifespan by 21% in the alpha strain [18423200] and by 33% in the remade strain [22377630].



Assays:
Mean: +21-33

Classification:

Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • RPL10A (9606)
  • RPL10A (9598)
  • RPL10A (9615)
  • RPL10A (9913)
  • LOC680700 (10116)
  • RPL10A (9031)
  • rpl10a (7955)
  • RpL10Ab (7227)
  • AgaP_AGAP011298 (7165)
  • rpl-1 (6239)
  • rpl101 (4896)
  • rpl102 (4896)
  • RPL1A (4932)
  • RPL1B (4932)
  • KLLA0B02002g (28985)
  • AGOS_AFL116W (33169)
  • GeneID:2678194 (148305)
  • NCU00294 (5141)
  • AT5G22440 (3702)
  • AT1G08360 (3702)
  • PGY1 (3702)
  • Os01g0860300 (4530)
  • Os02g0321900 (4530)
  • PF14_0391 (5833)



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