Cdk5

Symbol: Cdk5
Name: Cyclin-dependent kinase 5
Entrez gene ID: 36727
Ensembl gene ID: FBgn0013762
Species: Fly (Taxid: 7227)

Functional description:
Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Possible regulator of neuronal differentiation and/or development (By similarity). [UniProt]

Observation:

Cdk5 loss-of-function mutations result in defective axon guidance, age-dependent behavioral deficits and reduced lifespan by about one third [17368005].



Interventions:
  • Cdk5 mutation

  • Assays: Organismal Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • CDK5 (9606)
  • CDK5 (9598)
  • CDK5 (9615)
  • CDK5 (9913)
  • Cdk5 (10090)
  • Cdk5 (10116)
  • cdk5 (7955)
  • Cdk5 (7227)
  • AgaP_AGAP005772 (7165)
  • cdk-5 (6239)
  • pef1 (4896)
  • PHO85 (4932)
  • KLLA0D11990g (28985)
  • AGOS_AGL242C (33169)
  • GeneID:2678137 (148305)
  • NCU07580 (5141)

  • Inparanoids
  • FBpp0086483 (7227)
  • ENSMUSP00000030814 (10090)
  • ENSRNOP00000011052 (10116)
  • ENSMMUP00000026930 (9544)
  • ENSP00000297518 (9606)



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