PIB1

Symbol: PIB1
Name: PhosphatidylInositol(3)-phosphate Binding 1
Entrez gene ID: 851908
Ensembl gene ID: YDR313C
Species: Yeast (Taxid: 4932)

Functional description:
Pib1p; RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain [Source:SGD;Acc:S000002721] [Ensembl]

Observation:

Deletion of PIB1 increases replicative lifespan by 25% in the alpha strain [16293764; 19030232].



Interventions:
  • PIB1 deletion +25%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • SPBC36B7.05c (4896)
  • PIB1 (4932)
  • KLLA0C14542g (28985)
  • AGOS_AAL039C (33169)



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