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Symbol: MRS4 Name: Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs3p; functions under low-iron conditions; may transport other cations in addition to iron Entrez gene ID: 853926 Species: Yeast (Taxid: 4932) Functional description: Mrs4p; Iron transporter that mediates Fe2+ transport across the inner mitochondrial membrane; mitochondrial carrier family member, similar to and functionally redundant with Mrs3p; active under low-iron conditions; may transport other cations [Source:SGD;Acc:S000001760] [Ensembl] Observation: MRS4 deletion decreases mean replicative lifespan by 30% in the alpha strain and 40% in a strain [18340043; 19030232]. Interventions: Assays: Replicative Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Edit \ Update (Admin) | Delete |
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