Effect of superoxide dismutase deficiency on the life span of the yeast Saccharomyces cerevisiae. An oxygen-independent role of Cu,Zn-superoxide dismutase.

Authors: Wawryn J; Swieciło A; Bartosz G; Biliński T

Abstract: Effects of the absence of Cu,Zn-superoxide dismutase (CuZnSOD) on the replicative life span of the yeast Saccharomyces cerevisiae were studied under different oxygen conditions. In both strains, replicative life span and the rate of cell divisions were found to be similar under the atmosphere of air and under hypoxic (3% oxygen) and anoxic conditions. These results indicate that deleterious consequences of the lack of CuZnSOD are not limited to elevation of superoxide concentration and involve function(s) other than superoxide scavenging.

Keywords: Cell Division; Oxygen; Saccharomyces cerevisiae/enzymology/*physiology; Superoxide Dismutase/*deficiency

Journal: Biochimica et biophysica acta Volume: 1570 Issue: 3 Pages: 199-202 Date: May 22, 2002 PMID: 12020810

Select reference article to upload leave this field blank to prove your humanity

Citation:

Wawryn J, Swieciło A, Bartosz G, Biliński T (2002) Effect of superoxide dismutase deficiency on the life span of the yeast Saccharomyces cerevisiae. An oxygen-independent role of Cu,Zn-superoxide dismutase. Biochimica et biophysica acta 1570: 199-202.

Study

---

---

Back to top

---