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Denigma
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Lifespan
>
Interventions
>
YHC3 deletion
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Ontology of Gerontology
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YHC3 deletion
Species:
Budding yeast
(Taxid:
4932
)
Factor
:
YHC3
Manipulation:
Loss-of-Function
,
Knockout
,
Mutation
,
Deletion
Effect:
YHC3 deletion decreases 10-20% shortened lifespan [
16435200
].
Mean:
-10 to -20
References:
16435200: Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype.
Aging Relevance Analysis/Source:
GenAge
GenDR
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